MAPIYA contact map server for identification and visualization of molecular interactions in proteins and biological complexes.
Nucleic Acids Res
; 50(W1): W474-W482, 2022 07 05.
Article
em En
| MEDLINE
| ID: mdl-35524560
ABSTRACT
Correct identification and effective visualization of interactions in biomolecular structures facilitate understanding of their functions and molecular design. In response to the practical needs of structure-based analysis, we have created a Mapiya web server. The Mapiya integrates four main functionalities (i) generation of contact maps - intramolecular and intermolecular-for proteins, nucleic acids, and their complexes; (ii) characterization of the interactions physicochemical nature, (iii) interactive visualization of biomolecular conformations with automatic zoom on selected contacts using Molstar and (iv) additional sequence- and structure-based analyses performed with third-party software and in-house algorithms combined into an easy-to-use interface. Thus, Mapiya offers a highly customized analysis of the molecular interactions' in various biological systems. The web server is available at http//mapiya.lcbio.pl/.
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1
Base de dados:
MEDLINE
Assunto principal:
Software
/
Proteínas
Tipo de estudo:
Diagnostic_studies
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article