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Thromboxane A2 receptor activation via Gα13-RhoA/C-ROCK-LIMK2-dependent signal transduction inhibits angiogenic sprouting of human endothelial cells.
Eckenstaler, Robert; Ripperger, Anne; Hauke, Michael; Braun, Heike; Ergün, Süleyman; Schwedhelm, Edzard; Benndorf, Ralf A.
Afiliação
  • Eckenstaler R; Martin-Luther-University Halle-Wittenberg, Department of Clinical Pharmacy and Pharmacotherapy, Halle (Saale), Germany.
  • Ripperger A; Martin-Luther-University Halle-Wittenberg, Department of Clinical Pharmacy and Pharmacotherapy, Halle (Saale), Germany.
  • Hauke M; Martin-Luther-University Halle-Wittenberg, Department of Clinical Pharmacy and Pharmacotherapy, Halle (Saale), Germany.
  • Braun H; Martin-Luther-University Halle-Wittenberg, Department of Clinical Pharmacy and Pharmacotherapy, Halle (Saale), Germany.
  • Ergün S; Institute of Anatomy and Cell Biology, Julius-Maximilians-University, Würzburg, Germany.
  • Schwedhelm E; Institute of Clinical Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Benndorf RA; Martin-Luther-University Halle-Wittenberg, Department of Clinical Pharmacy and Pharmacotherapy, Halle (Saale), Germany. Electronic address: ralf.benndorf@pharmazie.uni-halle.de.
Biochem Pharmacol ; 201: 115069, 2022 07.
Article em En | MEDLINE | ID: mdl-35525325
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína rhoA de Ligação ao GTP / Subunidades alfa G12-G13 de Proteínas de Ligação ao GTP / Receptores de Tromboxano A2 e Prostaglandina H2 / Quinases Lim / Células Endoteliais da Veia Umbilical Humana Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína rhoA de Ligação ao GTP / Subunidades alfa G12-G13 de Proteínas de Ligação ao GTP / Receptores de Tromboxano A2 e Prostaglandina H2 / Quinases Lim / Células Endoteliais da Veia Umbilical Humana Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article