Pre-existing T cell immunity determines the frequency and magnitude of cellular immune response to two doses of mRNA vaccine against SARS-CoV-2.

Casado, José L; Vizcarra, Pilar; Haemmerle, Johannes; Velasco, Héctor; Martín-Hondarza, Adrián; Rodríguez-Domínguez, Mario J; Velasco, Tamara; Martín, Sara; Romero-Hernández, Beatriz; Fernández-Escribano, Marina; Vallejo, Alejandro.

Afiliação

Casado JL; Department of Infectious Diseases, Hospital Universitario Ramon y Cajal, Madrid, Spain.
Vizcarra P; Department of Infectious Diseases, Hospital Universitario Ramon y Cajal, Madrid, Spain.
Haemmerle J; Department of Prevention of Occupational Risks, Hospital Universitario Ramon y Cajal, Madrid, Spain.
Velasco H; Laboratory of Immunovirology, Department of Infectious Diseases, Health Research Institute Ramon y Cajal (IRyCIS), Hospital Universitario Ramon y Cajal, Madrid, Spain.
Martín-Hondarza A; Laboratory of Immunovirology, Department of Infectious Diseases, Health Research Institute Ramon y Cajal (IRyCIS), Hospital Universitario Ramon y Cajal, Madrid, Spain.
Rodríguez-Domínguez MJ; Department of Microbiology, Health Research Institute Ramon y Cajal (IRyCIS), CIBERESP, Hospital Universitario Ramon y Cajal, Madrid, Spain.
Velasco T; Department of Infectious Diseases, Hospital Universitario Ramon y Cajal, Madrid, Spain.
Martín S; Department of Infectious Diseases, Hospital Universitario Ramon y Cajal, Madrid, Spain.
Romero-Hernández B; Department of Microbiology, Health Research Institute Ramon y Cajal (IRyCIS), CIBERESP, Hospital Universitario Ramon y Cajal, Madrid, Spain.
Fernández-Escribano M; Department of Prevention of Occupational Risks, Hospital Universitario Ramon y Cajal, Madrid, Spain.
Vallejo A; Department of Infectious Diseases, Hospital Universitario Ramon y Cajal, Madrid, Spain.

Vaccine X ; 11: 100165, 2022 Aug.

Article em En | MEDLINE | ID: mdl-35529539

Palavras-chave

AU, arbitrary units; CLIA, chemoluminiscent immunoassay; COVID-19, Coronavirus disease 2019; Cellular response; IgG, immunoglobulin G; Pre-existing immunity; RT-PCR, retrotranscriptasepolymerase chain reaction; S protein, Spike protein; SARS-CoV-2 humoral response; SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2; mRNA vaccine

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article