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TDP-43 Proteinopathy Presenting with Typical Symptoms of Parkinson's Disease.
Yamashita, Rika; Beck, Goichi; Yonenobu, Yuki; Inoue, Kimiko; Mitsutake, Akihiko; Ishiura, Hiroyuki; Hasegawa, Masato; Murayama, Shigeo; Mochizuki, Hideki.
Afiliação
  • Yamashita R; Department of Neurology, Osaka University Graduate School of Medicine, Suita, Japan.
  • Beck G; Department of Neurology, Osaka University Graduate School of Medicine, Suita, Japan.
  • Yonenobu Y; Department of Neurology, Osaka University Graduate School of Medicine, Suita, Japan.
  • Inoue K; Department of Neurology, NHO Osaka Toneyama Medical Center, Toyonaka, Japan.
  • Mitsutake A; Department of Neurology, The University of Tokyo, Tokyo, Japan.
  • Ishiura H; Department of Neurology, The University of Tokyo, Tokyo, Japan.
  • Hasegawa M; Dementia Research Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
  • Murayama S; Department of Neurology, Osaka University Graduate School of Medicine, Suita, Japan.
  • Mochizuki H; Department of Neurology and Neuropathology (Brain Bank for Aging Research), Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan.
Mov Disord ; 37(7): 1561-1563, 2022 07.
Article em En | MEDLINE | ID: mdl-35531755
ABSTRACT
Accumulation of abnormal transactivation response DNA-binding protein of 43 kDa (TDP-43) independently induces dopaminergic neuronal loss in the substantia nigra without Lewy pathology, and results in typical Parkinson's disease-like motor symptoms.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Proteinopatias TDP-43 Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Proteinopatias TDP-43 Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article