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Filaggrin-deficient rats generated using zinc-finger nucleases spontaneously exhibit dry scaly skin.
Nakashima, Chisa; Doi, Hiromi; Nakajima, Saeko; Mashimo, Tomoji; Oga, Toru; Ishida-Yamamoto, Akemi; Honda, Tetsuya; Ishida, Yoshihiro; Otsuka, Atsushi; Kabashima, Kenji.
Afiliação
  • Nakashima C; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Department of Dermatology, Faculty of Medicine, Kindai University Hospital, Osaka, Japan.
  • Doi H; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
  • Nakajima S; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Department of Drug Discovery for Inflammatory Skin Diseases, Kyoto University Graduate School of Medicine, Kyoto, Japan.
  • Mashimo T; Division of Animal Genetics, Laboratory Animal Research Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Oga T; Department of Respiratory Care and Sleep Control Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Ishida-Yamamoto A; Department of Dermatology, Asahikawa Medical University, Hokkaido, Japan.
  • Honda T; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu, Japan.
  • Ishida Y; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
  • Otsuka A; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Department of Dermatology, Faculty of Medicine, Kindai University Hospital, Osaka, Japan; Translational Research Department for Skin and Brain Diseases, Kyoto University Graduate School of Medicine, Kyoto, Japan.
  • Kabashima K; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Singapore Immunology Network (SIgN) and Skin Research Institute of Singapore (SRIS), Agency for Science, Technology and Research (A∗STAR), Biopolis, Singapore. Electronic address: kaba@kuhp.kyoto-u.ac.jp.
Allergol Int ; 71(4): 545-547, 2022 10.
Article em En | MEDLINE | ID: mdl-35545489
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nucleases de Dedos de Zinco / Proteínas Filagrinas Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nucleases de Dedos de Zinco / Proteínas Filagrinas Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article