Novel oligopeptide nanoprobe for targeted cancer cell imaging.
RSC Adv
; 8(54): 30887-30893, 2018 Aug 30.
Article
em En
| MEDLINE
| ID: mdl-35548769
ABSTRACT
Here we designed and constructed a tryptophan-phenylalanine-phenylalanine-tryptophan (WFFW) tetrapeptide, which generated photostable and tunable fluorescence emission signals from 340 nm to 500 nm. The WFFW tetrapeptide could self-assemble into a spherical nanostructure with enhanced fluorescence intensity. Driven by π-π stacking and hydrogen bond interaction, WFFW co-assembled with arginine-glycine-aspartic acid (RGD) modified WFFW to form a cancer-targeted fluorescent nanoprobe, which could selectively image the cancer cells.
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MEDLINE
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En
Ano de publicação:
2018
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Article