Proteome reallocation enables the selective de novo biosynthesis of non-linear, branched-chain acetate esters.

Seo, Hyeongmin; Giannone, Richard J; Yang, Yung-Hun; Trinh, Cong T

Seo, Hyeongmin; Giannone, Richard J; Yang, Yung-Hun; Trinh, Cong T.

Afiliação

Seo H; Department of Chemical and Biomolecular Engineering, The University of Tennessee, Knoxville, TN, USA; Center of Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN, USA.
Giannone RJ; Center of Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN, USA; Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, 37830, USA.
Yang YH; Department of Biological Engineering, Konkuk University, Seoul, South Korea.
Trinh CT; Department of Chemical and Biomolecular Engineering, The University of Tennessee, Knoxville, TN, USA; Center of Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN, USA. Electronic address: ctrinh@utk.edu.

Metab Eng ; 73: 38-49, 2022 09.

Article em En | MEDLINE | ID: mdl-35561848

Assuntos

Ésteres; Proteoma; Acetatos/metabolismo; Álcoois/metabolismo; Aminoácidos/genética; Carbono; Ésteres/metabolismo; Cetoácidos/metabolismo; Proteoma/genética

Palavras-chave

Escherichia coli; Ester biosynthesis; Isoamyl acetate; Isobutyl acetate; Metabolic burden; Modular design; Pathway selectivity; Proteome reallocation; Proteomics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteoma / Ésteres Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

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PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteoma / Ésteres Idioma: En Ano de publicação: 2022 Tipo de documento: Article