NGF Modulates Cholesterol Metabolism and Stimulates ApoE Secretion in Glial Cells Conferring Neuroprotection against Oxidative Stress.

Colardo, Mayra; Petraroia, Michele; Lerza, Letizia; Pensabene, Daniele; Martella, Noemi; Pallottini, Valentina; Segatto, Marco

Colardo, Mayra; Petraroia, Michele; Lerza, Letizia; Pensabene, Daniele; Martella, Noemi; Pallottini, Valentina; Segatto, Marco.

Afiliação

Colardo M; Department of Biosciences and Territory, University of Molise, Contrada Fonte Lappone, 86090 Pesche, Italy.
Petraroia M; Department of Biosciences and Territory, University of Molise, Contrada Fonte Lappone, 86090 Pesche, Italy.
Lerza L; Department of Biosciences and Territory, University of Molise, Contrada Fonte Lappone, 86090 Pesche, Italy.
Pensabene D; Department of Science, University Roma Tre, Viale Marconi 446, 00146 Rome, Italy.
Martella N; Department of Biosciences and Territory, University of Molise, Contrada Fonte Lappone, 86090 Pesche, Italy.
Pallottini V; Department of Science, University Roma Tre, Viale Marconi 446, 00146 Rome, Italy.
Segatto M; Neuroendocrinology Metabolism and Neuropharmacology Unit, IRCSS Fondazione Santa Lucia, Via del Fosso Fiorano 64, 00143 Rome, Italy.

Int J Mol Sci ; 23(9)2022 Apr 27.

Article em En | MEDLINE | ID: mdl-35563230

Assuntos

Fator de Crescimento Neural; Neuroproteção; Apolipoproteínas E/metabolismo; Astrócitos/metabolismo; Células Cultivadas; Colesterol/metabolismo; Fator de Crescimento Neural/metabolismo; Fator de Crescimento Neural/farmacologia; Neuroglia/metabolismo; Estresse Oxidativo

Palavras-chave

ApoE; astrocyte; cholesterol; differentiation; metabolism; nerve growth factor; neuron; reactive oxygen species; rotenone

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator de Crescimento Neural / Neuroproteção Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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