Histone renegades: Unusual H2A histone variants in plants and animals.
Semin Cell Dev Biol
; 135: 35-42, 2023 02 15.
Article
em En
| MEDLINE
| ID: mdl-35570098
ABSTRACT
H2A variants are histones that carry out specialized nucleosome function during the eukaryote genome packaging. Most genes encoding H2A histone variants arose in the distant past, and have highly conserved domains and structures. Yet, novel H2A variants have continued to arise throughout the radiation of eukaryotes and disturbed the apparent tranquility of nucleosomes. These species-specific H2A variants contributed to the functional diversification of nucleosomes through changes in both their structure and expression patterns. In this short review, we discuss the evolutionary trajectories of these histone renegades in plants and animal genomes.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Histonas
/
Nucleossomos
Limite:
Animals
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article