Reversible regulation of Cas12a activities by AcrVA5-mediated acetylation and CobB-mediated deacetylation.

Kang, Xiaoman; Yin, Lei; Zhuang, Songkuan; Hu, Tianshuai; Wu, Zhile; Zhao, Guoping; Chen, Yijian; Xu, Yong; Wang, Jin.

Afiliação

Kang X; CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, China.
Yin L; University of Chinese Academy of Sciences, Beijing, China.
Zhuang S; Tolo Biotechnology Company Limited, Shanghai, China.
Hu T; Department of Clinical Laboratory, Shenzhen Second People's Hospital & Institute of Translational Medicine/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China.
Wu Z; Department of Clinical Laboratory, Shenzhen Second People's Hospital & Institute of Translational Medicine/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China.
Zhao G; College of Life Sciences, Shanghai Normal University, Shanghai, China.
Chen Y; CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, China.
Xu Y; Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China. chenyijian@fudan.edu.cn.
Wang J; Key Laboratory of Clinical Pharmacology of Antibiotics, National Health Commission, Shanghai, China. chenyijian@fudan.edu.cn.

Cell Discov ; 8(1): 45, 2022 May 17.

Article em En | MEDLINE | ID: mdl-35581175

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article