Your browser doesn't support javascript.
loading
Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma.
Davidson, Shawn M; Schmidt, Daniel R; Heyman, Julia E; O'Brien, James P; Liu, Amy C; Israelsen, William J; Dayton, Talya L; Sehgal, Raghav; Bronson, Roderick T; Freinkman, Elizaveta; Mak, Howard H; Fanelli, Giuseppe Nicolò; Malstrom, Scott; Bellinger, Gary; Carracedo, Arkaitz; Pandolfi, Pier Paolo; Courtney, Kevin D; Jha, Abhishek; DePinho, Ronald A; Horner, James W; Thomas, Craig J; Cantley, Lewis C; Loda, Massimo; Vander Heiden, Matthew G.
Afiliação
  • Davidson SM; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.
  • Schmidt DR; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts.
  • Heyman JE; Broad Institute of MIT and Harvard University, Cambridge, Massachusetts.
  • O'Brien JP; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.
  • Liu AC; Broad Institute of MIT and Harvard University, Cambridge, Massachusetts.
  • Israelsen WJ; Beth Israel Deaconess Medical Center, Boston, Massachusetts.
  • Dayton TL; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.
  • Sehgal R; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.
  • Bronson RT; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.
  • Freinkman E; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.
  • Mak HH; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts.
  • Fanelli GN; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.
  • Malstrom S; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts.
  • Bellinger G; Elucidata, Cambridge, Massachusetts.
  • Carracedo A; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.
  • Pandolfi PP; Whitehead Institute, Cambridge, Massachusetts.
  • Courtney KD; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.
  • Jha A; Weill Cornell Medical College, New York, New York.
  • DePinho RA; Division of Pathology, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
  • Horner JW; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.
  • Thomas CJ; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.
  • Cantley LC; Beth Israel Deaconess Medical Center, Boston, Massachusetts.
  • Loda M; Beth Israel Deaconess Medical Center, Boston, Massachusetts.
  • Vander Heiden MG; Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Cancer Res ; 82(13): 2403-2416, 2022 07 05.
Article em En | MEDLINE | ID: mdl-35584006
SIGNIFICANCE: Differential expression of PKM1 and PKM2 impacts prostate tumorigenesis and suggests a potential therapeutic vulnerability in prostate cancer.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Adenocarcinoma Limite: Humans / Male Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Adenocarcinoma Limite: Humans / Male Idioma: En Ano de publicação: 2022 Tipo de documento: Article