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Homologous recombination deficiency (HRD) signature-3 in ovarian and uterine carcinosarcomas correlates with preclinical sensitivity to Olaparib, a poly (adenosine diphosphate [ADP]- ribose) polymerase (PARP) inhibitor.
Tymon-Rosario, Joan R; Manara, Paola; Manavella, Diego D; Bellone, Stefania; Hartwich, Tobias Max Philipp; Harold, Justin; Yang-Hartwich, Yang; Zipponi, Margherita; Choi, Jungmin; Jeong, Kyungjo; Mutlu, Levent; Yang, Kevin; Altwerger, Gary; Menderes, Gulden; Ratner, Elena; Huang, Gloria S; Clark, Mitchell; Andikyan, Vaagn; Azodi, Masoud; Schwartz, Peter E; Alexandrov, Ludmil B; Santin, Alessandro D.
Afiliação
  • Tymon-Rosario JR; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, United States of America.
  • Manara P; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, United States of America.
  • Manavella DD; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, United States of America.
  • Bellone S; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, United States of America.
  • Hartwich TMP; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, United States of America.
  • Harold J; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, United States of America.
  • Yang-Hartwich Y; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, United States of America.
  • Zipponi M; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, United States of America.
  • Choi J; Department of Biomedical Sciences, Korea University College of Medicine, 02841 Seoul, Republic of Korea; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, United States of America.
  • Jeong K; Department of Biomedical Sciences, Korea University College of Medicine, 02841 Seoul, Republic of Korea.
  • Mutlu L; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, United States of America.
  • Yang K; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, United States of America.
  • Altwerger G; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, United States of America.
  • Menderes G; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, United States of America.
  • Ratner E; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, United States of America.
  • Huang GS; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, United States of America.
  • Clark M; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, United States of America.
  • Andikyan V; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, United States of America.
  • Azodi M; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, United States of America.
  • Schwartz PE; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, United States of America.
  • Alexandrov LB; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, USA.
  • Santin AD; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, United States of America. Electronic address: alessandro.santin@yale.edu.
Gynecol Oncol ; 166(1): 117-125, 2022 07.
Article em En | MEDLINE | ID: mdl-35599167
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Carcinossarcoma Tipo de estudo: Diagnostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Carcinossarcoma Tipo de estudo: Diagnostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article