Ventilation-induced epithelial injury drives biological onset of lung trauma in vitro and is mitigated with prophylactic anti-inflammatory therapeutics.

Nof, Eliram; Artzy-Schnirman, Arbel; Bhardwaj, Saurabh; Sabatan, Hadas; Waisman, Dan; Hochwald, Ori; Gruber, Maayan; Borenstein-Levin, Liron; Sznitman, Josué

Nof, Eliram; Artzy-Schnirman, Arbel; Bhardwaj, Saurabh; Sabatan, Hadas; Waisman, Dan; Hochwald, Ori; Gruber, Maayan; Borenstein-Levin, Liron; Sznitman, Josué.

Afiliação

Nof E; Faculty of Biomedical Engineering Technion - Israel Institute of Technology Haifa Israel.
Artzy-Schnirman A; Faculty of Biomedical Engineering Technion - Israel Institute of Technology Haifa Israel.
Bhardwaj S; Faculty of Biomedical Engineering Technion - Israel Institute of Technology Haifa Israel.
Sabatan H; Faculty of Biomedical Engineering Technion - Israel Institute of Technology Haifa Israel.
Waisman D; Faculty of Medicine Technion - Israel Institute of Technology Haifa Israel.
Hochwald O; Department of Neonatology Carmel Medical Center Haifa Israel.
Gruber M; Faculty of Medicine Technion - Israel Institute of Technology Haifa Israel.
Borenstein-Levin L; Department of Neonatology Ruth Rappaport Children's Hospital, Rambam Healthcare Haifa Israel.
Sznitman J; Azrieli Faculty of Medicine Bar-Ilan University Safed Israel.

Bioeng Transl Med ; 7(2): e10271, 2022 May.

Article em En | MEDLINE | ID: mdl-35600654

Palavras-chave

drug testing; epithelial cells; inflammation; lung; preclinical in vitro model; respiratory distress; ventilation

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Guideline Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Guideline Idioma: En Ano de publicação: 2022 Tipo de documento: Article