Low-Level Cefepime Exposure Induces High-Level Resistance in Environmental Bacteria: Molecular Mechanism and Evolutionary Dynamics.

Wang, Hanqing; Feng, Youjun; Lu, Huijie

Wang, Hanqing; Feng, Youjun; Lu, Huijie.

Afiliação

Wang H; College of Environmental and Resource Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, China.
Feng Y; Departments of Microbiology & General Intensive Care Unit of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.
Lu H; College of Environmental and Resource Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, China.

Environ Sci Technol ; 56(21): 15074-15083, 2022 11 01.

Article em En | MEDLINE | ID: mdl-35608924

Assuntos

Antibacterianos; Bactérias; Cefepima/farmacologia; Testes de Sensibilidade Microbiana; Antibacterianos/farmacologia; Resistência Microbiana a Medicamentos/genética; Farmacorresistência Bacteriana/genética

Palavras-chave

agent-based modeling; antibiotic resistance; evolutionary dynamics; fitness landscape; modified Moran process

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bactérias / Antibacterianos Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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