Role of human organic cation transporter-1 (OCT-1/SLC22A1) in modulating the response to metformin in patients with type 2 diabetes.

Kawoosa, Fizalah; Shah, Zafar A; Masoodi, Shariq R; Amin, Asif; Rasool, Roohi; Fazili, Khalid M; Dar, Abid Hamid; Lone, Asif; Ul Bashir, Samir

Kawoosa, Fizalah; Shah, Zafar A; Masoodi, Shariq R; Amin, Asif; Rasool, Roohi; Fazili, Khalid M; Dar, Abid Hamid; Lone, Asif; Ul Bashir, Samir.

Afiliação

Kawoosa F; Department of Immunology and Molecular Medicine, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, 190011, India.
Shah ZA; Department of Immunology and Molecular Medicine, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, 190011, India. zafaraminshah00@gmail.com.
Masoodi SR; Department of Endocrinology, Sher-I-Kashmir Institute of Medical Sciences, Soura, Srinagar, Jammu and Kashmir, 190011, India.
Amin A; Department of Biotechnology, University of Kashmir, Srinagar, Jammu and Kashmir, 190006, India.
Rasool R; Department of Immunology and Molecular Medicine, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, 190011, India.
Fazili KM; Department of Biotechnology, University of Kashmir, Srinagar, Jammu and Kashmir, 190006, India.
Dar AH; Department of Biotechnology, Central University of Kashmir, Ganderbal, Jammu and Kashmir, 191201, India.
Lone A; Department of Biochemistry, Deshbandhu College, University of Delhi, Delhi, 110019, India.
Ul Bashir S; Department of Chemistry, University of Northern British Columbia, Prince George, Canada.

BMC Endocr Disord ; 22(1): 140, 2022 May 26.

Article em En | MEDLINE | ID: mdl-35619086

Assuntos

Diabetes Mellitus Tipo 2; Metformina; Cátions/metabolismo; Diabetes Mellitus Tipo 2/tratamento farmacológico; Diabetes Mellitus Tipo 2/genética; Humanos; Hipoglicemiantes/farmacologia; Hipoglicemiantes/uso terapêutico; Metformina/farmacologia; Metformina/uso terapêutico; Simulação de Acoplamento Molecular; Transportador 1 de Cátions Orgânicos/genética; Transportador 1 de Cátions Orgânicos/metabolismo; Polimorfismo de Nucleotídeo Único

Palavras-chave

AMPK; Metformin; Organic cation transporter 1(OCT-1/SLC22A1)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 2 / Metformina Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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