Synergistic effects of trans-p-coumaric acid isolated from the ethanol extract of Gynura procumbens in promoting intestinal absorption of chlorogenic acid and reversing alcoholic fatty liver disease.

Wang, Cong; Huang, Xia-Ling; Mu, Yun-Mei; Li, Yu-Sang; He, Yu-Min; Tang, He-Bin

Wang, Cong; Huang, Xia-Ling; Mu, Yun-Mei; Li, Yu-Sang; He, Yu-Min; Tang, He-Bin.

Afiliação

Wang C; Lab of Hepatopharmacology and Ethnopharmacology, School of Pharmaceutical Sciences, South-central Minzu University, No. 182, Minyuan Road, Wuhan, 430074, China. Electronic address: 1363994559@qq.com.
Huang XL; Lab of Hepatopharmacology and Ethnopharmacology, School of Pharmaceutical Sciences, South-central Minzu University, No. 182, Minyuan Road, Wuhan, 430074, China. Electronic address: hxl806877686@sina.com.
Mu YM; Lab of Hepatopharmacology and Ethnopharmacology, School of Pharmaceutical Sciences, South-central Minzu University, No. 182, Minyuan Road, Wuhan, 430074, China. Electronic address: 813331282@qq.com.
Li YS; Lab of Hepatopharmacology and Ethnopharmacology, School of Pharmaceutical Sciences, South-central Minzu University, No. 182, Minyuan Road, Wuhan, 430074, China. Electronic address: liys2006@mail.scuec.edu.cn.
He YM; Medical College of China Three Gorges University, Yichang, 443002, China. Electronic address: hym0811@163.com.
Tang HB; Lab of Hepatopharmacology and Ethnopharmacology, School of Pharmaceutical Sciences, South-central Minzu University, No. 182, Minyuan Road, Wuhan, 430074, China. Electronic address: hbtang2006@mail.scuec.edu.cn.

J Ethnopharmacol ; 295: 115407, 2022 Sep 15.

Article em En | MEDLINE | ID: mdl-35640740

Assuntos

Asteraceae; Fígado Gorduroso Alcoólico; Fígado Gorduroso; Animais; Asteraceae/química; Ácido Clorogênico/uso terapêutico; Ácidos Cumáricos; Etanol/química; Fígado Gorduroso/tratamento farmacológico; Fígado Gorduroso Alcoólico/metabolismo; Absorção Intestinal; Fígado; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Extratos Vegetais/farmacologia; Extratos Vegetais/uso terapêutico; Ácido Quínico/farmacologia; Ratos

Palavras-chave

Alcoholic fatty liver disease; Chlorogenic acid; Gynura procumbens; Single-pass intestinal perfusion; Trans-p-coumaric acid

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Asteraceae / Fígado Gorduroso / Fígado Gorduroso Alcoólico Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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