A minimal bile salt excretory pump promoter allows bile acid-driven physiological regulation of transgene expression from a gene therapy vector.

Martínez-García, Javier; Molina, Manuela; Odriozola, Leticia; Molina, Angie; González-Aseguinolaza, Gloria; Weber, Nicholas D; Smerdou, Cristian.

Afiliação

Martínez-García J; Division of Gene Therapy and Regulation of Gene Expression, Cima Universidad de Navarra, Av. Pio XII 55, 31008, Pamplona, Spain.
Molina M; Division of Gene Therapy and Regulation of Gene Expression, Cima Universidad de Navarra, Av. Pio XII 55, 31008, Pamplona, Spain.
Odriozola L; Division of Gene Therapy and Regulation of Gene Expression, Cima Universidad de Navarra, Av. Pio XII 55, 31008, Pamplona, Spain.
Molina A; Division of Gene Therapy and Regulation of Gene Expression, Cima Universidad de Navarra, Av. Pio XII 55, 31008, Pamplona, Spain.
González-Aseguinolaza G; Division of Gene Therapy and Regulation of Gene Expression, Cima Universidad de Navarra, Av. Pio XII 55, 31008, Pamplona, Spain.
Weber ND; Instituto de Investigación Sanitaria de Navarra (IdISNA), Pamplona, Spain.
Smerdou C; Vivet Therapeutics S.L., Calle Arcadio María Larraona, 1 - 2ª planta, 31008, Pamplona, Spain.

Cell Biosci ; 12(1): 79, 2022 May 31.

Article em En | MEDLINE | ID: mdl-35641984