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Protocol paper: a multi-center, double-blinded, randomized, 6-month, placebo-controlled study followed by 12-month open label extension to evaluate the safety and efficacy of Saracatinib in Fibrodysplasia Ossificans Progressiva (STOPFOP).
Smilde, Bernard J; Stockklausner, Clemens; Keen, Richard; Whittaker, Andrew; Bullock, Alex N; von Delft, Annette; van Schoor, Natasja M; Yu, Paul B; Eekhoff, E Marelise W.
Afiliação
  • Smilde BJ; Department of Internal Medicine Section Endocrinology, Amsterdam UMC location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081HV, Amsterdam, The Netherlands.
  • Stockklausner C; Tissue Function and Regeneration, Amsterdam Movement Sciences, Amsterdam, The Netherlands.
  • Keen R; Department of Paediatrics, Klinikum Garmisch-Partenkirchen, Garmisch Partenkirchen, Germany.
  • Whittaker A; Department of Rheumatology, Royal National Orthopaedic Hospital, London, UK.
  • Bullock AN; Emerging Innovations Unit, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
  • von Delft A; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • van Schoor NM; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Yu PB; Oxford Biomedical Research Centre, National Institute for Health Research, University of Oxford, Oxford, UK.
  • Eekhoff EMW; Epidemiology and Data Science, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
BMC Musculoskelet Disord ; 23(1): 519, 2022 Jun 01.
Article em En | MEDLINE | ID: mdl-35650602
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Texto completo: 1 Eixos temáticos: Pesquisa_clinica Base de dados: MEDLINE Assunto principal: Quinazolinas / Benzodioxóis / Miosite Ossificante Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adolescent / Adult / Aged / Humans / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article
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Texto completo: 1 Eixos temáticos: Pesquisa_clinica Base de dados: MEDLINE Assunto principal: Quinazolinas / Benzodioxóis / Miosite Ossificante Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adolescent / Adult / Aged / Humans / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article