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Transient expression of an adenine base editor corrects the Hutchinson-Gilford progeria syndrome mutation and improves the skin phenotype in mice.
Whisenant, Daniel; Lim, Kayeong; Revêchon, Gwladys; Yao, Haidong; Bergo, Martin O; Machtel, Piotr; Kim, Jin-Soo; Eriksson, Maria.
Afiliação
  • Whisenant D; Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Huddinge, Sweden.
  • Lim K; Center for Genome Engineering, Institute for Basic Science (IBS), Dajeon, South Korea.
  • Revêchon G; Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Huddinge, Sweden.
  • Yao H; Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Huddinge, Sweden.
  • Bergo MO; Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Huddinge, Sweden.
  • Machtel P; Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Huddinge, Sweden.
  • Kim JS; Center for Genome Engineering, Institute for Basic Science (IBS), Dajeon, South Korea.
  • Eriksson M; Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Huddinge, Sweden. maria.eriksson.2@ki.se.
Nat Commun ; 13(1): 3068, 2022 06 02.
Article em En | MEDLINE | ID: mdl-35654881
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Progéria Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Progéria Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article