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Multi-echo balanced SSFP with a sequential phase-encoding order for functional MR imaging at 7T.
Liang, Huilou; Pan, Ziyi; Qian, Chencan; Liu, Chengwen; Sun, Kaibao; Weng, Dehe; An, Jing; Zhuo, Yan; Wang, Danny J J; Guo, Hua; Xue, Rong.
Afiliação
  • Liang H; State Key Laboratory of Brain and Cognitive Science, Beijing MRI Center for Brain Research, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
  • Pan Z; University of Chinese Academy of Sciences, Beijing, China.
  • Qian C; Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China.
  • Liu C; State Key Laboratory of Brain and Cognitive Science, Beijing MRI Center for Brain Research, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
  • Sun K; University of Chinese Academy of Sciences, Beijing, China.
  • Weng D; Medical Psychological Center, the Second Xiangya Hospital, Central South University, Changsha, China.
  • An J; State Key Laboratory of Brain and Cognitive Science, Beijing MRI Center for Brain Research, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
  • Zhuo Y; Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China.
  • Wang DJJ; Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China.
  • Guo H; State Key Laboratory of Brain and Cognitive Science, Beijing MRI Center for Brain Research, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
  • Xue R; University of Chinese Academy of Sciences, Beijing, China.
Magn Reson Med ; 88(3): 1303-1313, 2022 09.
Article em En | MEDLINE | ID: mdl-35657055
PURPOSE: To develop a 2D multi-echo passband balanced SSFP (bSSFP) sequence using an echo-train readout with a sequential phase-encoding order (sequential multi-echo bSSFP), and evaluate its performance in fast functional brain imaging at 7 T. METHODS: As images of sequential multi-echo bSSFP exhibit multiple ghosts due to periodic k-space modulations, a GRAPPA-based reconstruction method was proposed to eliminate ghosting artifacts. MRI experiments were performed to compare the image quality of multi-echo bSSFP and conventional single-echo bSSFP. Submillimeter-resolution fMRI using a checkerboard visual stimulus was conducted to compare the activation characteristics of multi-echo bSSFP, conventional single-echo bSSFP and standard gradient-echo EPI (GE-EPI). RESULTS: A higher mean structural similarity index was found between images of single-echo bSSFP and multi-echo bSSFP with a shorter echo train length (ETL). Multi-echo bSSFP (ETL = 3) showed higher temporal SNR (tSNR) values than GRAPPA-accelerated single-echo bSSFP (R = 2). In submillimeter-resolution fMRI experiments, multi-echo bSSFP (ETL = 3) approached the imaging speed of GRAPPA-accelerated single-echo bSSFP (R = 2), but without tSNR penalty and reduced activation due to acceleration. The median t-value and the number of significantly activated voxels were comparable between GE-EPI and multi-echo bSSFP (ETL = 3) that provides virtually distortion-free functional images and inherits the activation patterns of conventional bSSFP. CONCLUSION: Sequential multi-echo bSSFP (ETL = 3) is suitable for fast fMRI with submillimeter in-plane resolution, and offers an option to accelerate bSSFP imaging without tSNR penalty like parallel imaging.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imageamento por Ressonância Magnética / Imagem Ecoplanar Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imageamento por Ressonância Magnética / Imagem Ecoplanar Idioma: En Ano de publicação: 2022 Tipo de documento: Article