TSP1 promotes fibroblast proliferation and extracellular matrix deposition via the IL6/JAK2/STAT3 signalling pathway in keloids.

Feng, Qing-Lan; Gu, Jing-Jing; Chen, Jun-Yi; Zheng, Wen-Yue; Pan, Hui-Hui; Xu, Xue-Yan; Deng, Cheng-Cheng; Yang, Bin

Feng, Qing-Lan; Gu, Jing-Jing; Chen, Jun-Yi; Zheng, Wen-Yue; Pan, Hui-Hui; Xu, Xue-Yan; Deng, Cheng-Cheng; Yang, Bin.

Afiliação

Feng QL; The First School of Clinical Medicine, Southern Medical University, Guangzhou, China.
Gu JJ; Dermatology Hospital, Southern Medical University, Guangzhou, China.
Chen JY; The First School of Clinical Medicine, Southern Medical University, Guangzhou, China.
Zheng WY; Dermatology Hospital, Southern Medical University, Guangzhou, China.
Pan HH; The First School of Clinical Medicine, Southern Medical University, Guangzhou, China.
Xu XY; Dermatology Hospital, Southern Medical University, Guangzhou, China.
Deng CC; The First School of Clinical Medicine, Southern Medical University, Guangzhou, China.
Yang B; Dermatology Hospital, Southern Medical University, Guangzhou, China.

Exp Dermatol ; 31(10): 1533-1542, 2022 10.

Article em En | MEDLINE | ID: mdl-35661430

Assuntos

Queloide; Fatores de Transcrição de Zíper de Leucina e Hélice-Alça-Hélix Básicos; Proliferação de Células; Células Cultivadas; Colágeno/metabolismo; Colágeno Tipo I/metabolismo; Matriz Extracelular/metabolismo; Fibroblastos/metabolismo; Humanos; Interleucina-6/metabolismo; Janus Quinase 2/metabolismo; Queloide/metabolismo; Fator de Transcrição STAT3/metabolismo; Trombospondina 1/metabolismo

Palavras-chave

IL6; TSP1; collagen; fibroblast; keloid

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Queloide Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Queloide Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article