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Furin extracellularly cleaves secreted PTENα/ß to generate C-terminal fragment with a tumor-suppressive role.
Zhang, Cheng; Ma, Hong-Ming; Dong, Shuang-Shu; Zhang, Na; He, Ping; Ge, Meng-Kai; Xia, Li; Yu, Jian-Xiu; Xia, Qiang; Chen, Guo-Qiang; Shen, Shao-Ming.
Afiliação
  • Zhang C; Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), 200025, Shanghai, China.
  • Ma HM; Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), 200025, Shanghai, China.
  • Dong SS; Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), 200025, Shanghai, China.
  • Zhang N; State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 200031, Shanghai, China.
  • He P; Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), 200025, Shanghai, China.
  • Ge MK; State Key Laboratory of Oncogenes and Related Genes, and Chinese Academy of Medical Sciences Research Unit (NO .2019RU043), Renji hospital, SJTU-SM, 200127, Shanghai, China.
  • Xia L; Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), 200025, Shanghai, China.
  • Yu JX; Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), 200025, Shanghai, China.
  • Xia Q; Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), 200025, Shanghai, China.
  • Chen GQ; State Key Laboratory of Oncogenes and Related Genes, and Chinese Academy of Medical Sciences Research Unit (NO .2019RU043), Renji hospital, SJTU-SM, 200127, Shanghai, China.
  • Shen SM; Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), 200025, Shanghai, China. chengq@shsmu.edu.cn.
Cell Death Dis ; 13(6): 532, 2022 06 06.
Article em En | MEDLINE | ID: mdl-35668069
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Furina / Neoplasias Hepáticas Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Furina / Neoplasias Hepáticas Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article