What size cutoff level should be used to implement optical polyp diagnosis?
Endoscopy
; 54(12): 1182-1190, 2022 12.
Article
em En
| MEDLINE
| ID: mdl-35668663
ABSTRACT
BACKGROUND:
The risk of advanced pathology increases with polyp size, as does the potential for mismanagement when optical diagnosis is used. This study aimed to evaluate the proportion of patients who would be assigned inadequate surveillance intervals when different size cutoffs are adopted for use of optical diagnosis.METHODS:
In a post hoc analysis of three prospective studies, the use of optical diagnosis was evaluated for three polyp size groups 1-3, 1-5, and 1-10âmm. The primary outcome was the proportion of patients in whom advanced adenomas were found and optical diagnosis resulted in delayed surveillance. Secondary outcomes included agreements between surveillance intervals based on high confidence optical diagnosis and pathology outcomes, reduction in histopathological examinations, and proportion of patients who could receive an immediate surveillance recommendation.RESULTS:
We included 3374 patients (7291 polyps ≤â10âmm) undergoing complete colonoscopies (median age 66.0 years, 75.2â% male, 29.6â% for screening). The percentage of patients with advanced adenomas and either 2- or 7-year delayed surveillance intervals (nâ=â79) was 3.8â%, 15.2â%, and 25.3â% for size cutoffs of 1-3, 1-5, and 1-10âmm polyps, respectively (Pâ<â0.001). Surveillance interval agreements between pathology and optical diagnosis for the three groups were 97.2â%, 95.5â%, and 94.2â%, respectively. Total reductions in pathology examinations for the three groups were 33.5â%, 62.3â%, and 78.2â%, respectively.CONCLUSION:
A 3-mm cutoff for clinical implementation of optical diagnosis resulted in a very low risk of delayed management of advanced neoplasia while showing high surveillance interval agreement with pathology and a one-third reduction in overall requirement for pathology examinations.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Colorretais
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Adenoma
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Pólipos do Colo
Tipo de estudo:
Diagnostic_studies
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Guideline
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Observational_studies
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Screening_studies
Limite:
Aged
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Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article