Loss of famh-136/ FAM136A results in minor locomotion and behavioral changes in Caenorhabditis elegans.

ABSTRACT

Not much is known about FAM136A, a human gene that may be involved in Meniere's disease and is conserved throughout animals. To understand the function of famh-136 , the Caenorhabditis elegans ortholog of FAM136A, loss of function alleles of the gene were generated. We find that loss of famh-136 function results in minor but significant changes to the locomotion and behavior.