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Regulatory B cell repertoire defects predispose lung cancer patients to immune-related toxicity following checkpoint blockade.
Patel, Akshay J; Willsmore, Zena N; Khan, Naeem; Richter, Alex; Naidu, Babu; Drayson, Mark T; Papa, Sophie; Cope, Andrew; Karagiannis, Sophia N; Perucha, Esperanza; Middleton, Gary W.
Afiliação
  • Patel AJ; Institute of Immunology and Immunotherapy (III), College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
  • Willsmore ZN; St. John's Institute of Dermatology, School of Basic & Medical Biosciences, King's College London, Guy's Hospital, King's College London, London, SE1 9RT, UK.
  • Khan N; Institute of Immunology and Immunotherapy (III), College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
  • Richter A; Institute of Immunology and Immunotherapy (III), College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
  • Naidu B; Institute of Inflammation and Ageing (IIA), College of Medical Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
  • Drayson MT; Institute of Immunology and Immunotherapy (III), College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
  • Papa S; Immunoengineering Group, King's College London, London, SE1 9RT, UK.
  • Cope A; Department of Medical Oncology, Guy's and St Thomas' NHS Trust, London, SE1 9RT, UK.
  • Karagiannis SN; Centre for Inflammation Biology and Cancer Immunology, School of Immunology and Microbial Sciences, King's College London, London, SE1 1UL, UK.
  • Perucha E; Centre for Rheumatic Diseases, King's College London, SE1 1UL, London, UK.
  • Middleton GW; St. John's Institute of Dermatology, School of Basic & Medical Biosciences, King's College London, Guy's Hospital, King's College London, London, SE1 9RT, UK.
Nat Commun ; 13(1): 3148, 2022 06 07.
Article em En | MEDLINE | ID: mdl-35672305
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Linfócitos B Reguladores / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Linfócitos B Reguladores / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article