SM03, an Anti-CD22 Antibody, Converts <i>Cis</i>-to-<i>Trans</i> Ligand Binding of CD22 against &#945;2,6-Linked Sialic Acid Glycans and Immunomodulates Systemic Autoimmune Diseases.

Wong, Kin L; Li, Zhengdong; Ma, Felix; Wang, Dong; Song, Nan; Chong, Chi H; Luk, Ka K; Leung, Shui O

SM03, an Anti-CD22 Antibody, Converts Cis-to-Trans Ligand Binding of CD22 against α2,6-Linked Sialic Acid Glycans and Immunomodulates Systemic Autoimmune Diseases.

Wong, Kin L; Li, Zhengdong; Ma, Felix; Wang, Dong; Song, Nan; Chong, Chi H; Luk, Ka K; Leung, Shui O.

Afiliação

Wong KL; SinoMab BioScience Ltd., Hong Kong Special Administrative Region, China indy.wong@sinomab.com shawn@sinomab.com.
Li Z; SinoMab BioScience Ltd., Hong Kong Special Administrative Region, China.
Ma F; SinoMab BioScience Ltd., Hong Kong Special Administrative Region, China.
Wang D; SinoMab BioScience Ltd., Hong Kong Special Administrative Region, China.
Song N; SinoMab BioScience Ltd., Hong Kong Special Administrative Region, China.
Chong CH; SinoMab BioScience Ltd., Hong Kong Special Administrative Region, China.
Luk KK; SinoMab BioScience Ltd., Hong Kong Special Administrative Region, China.
Leung SO; SinoMab BioScience Ltd., Hong Kong Special Administrative Region, China indy.wong@sinomab.com shawn@sinomab.com.

J Immunol ; 208(12): 2726-2737, 2022 06 15.

Article em En | MEDLINE | ID: mdl-35688465

Assuntos

Artrite Reumatoide; Lúpus Eritematoso Sistêmico; Artrite Reumatoide/terapia; Humanos; Ligantes; Ácido N-Acetilneuramínico; Polissacarídeos; Receptores de Antígenos de Linfócitos B; Lectina 2 Semelhante a Ig de Ligação ao Ácido Siálico; Ácidos Siálicos

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Lúpus Eritematoso Sistêmico Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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