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Absence of microglia promotes diverse pathologies and early lethality in Alzheimer's disease mice.
Kiani Shabestari, Sepideh; Morabito, Samuel; Danhash, Emma Pascal; McQuade, Amanda; Sanchez, Jessica Ramirez; Miyoshi, Emily; Chadarevian, Jean Paul; Claes, Christel; Coburn, Morgan Alexandra; Hasselmann, Jonathan; Hidalgo, Jorge; Tran, Kayla Nhi; Martini, Alessandra C; Chang Rothermich, Winston; Pascual, Jesse; Head, Elizabeth; Hume, David A; Pridans, Clare; Davtyan, Hayk; Swarup, Vivek; Blurton-Jones, Mathew.
Afiliação
  • Kiani Shabestari S; Department of Neurobiology & Behavior, UC Irvine, Irvine, CA 92697, USA; Sue and Bill Gross Stem Cell Research Center, UC Irvine, Irvine, CA 92697, USA.
  • Morabito S; Mathematical, Computational and System Biology (MCSB) Program, UC Irvine, Irvine, CA 92697, USA; Institute for Memory Impairments and Neurological Disorders, UC Irvine, Irvine, CA 92697, USA.
  • Danhash EP; Sue and Bill Gross Stem Cell Research Center, UC Irvine, Irvine, CA 92697, USA.
  • McQuade A; Department of Neurobiology & Behavior, UC Irvine, Irvine, CA 92697, USA; Sue and Bill Gross Stem Cell Research Center, UC Irvine, Irvine, CA 92697, USA; Institute for Memory Impairments and Neurological Disorders, UC Irvine, Irvine, CA 92697, USA.
  • Sanchez JR; Department of Neurobiology & Behavior, UC Irvine, Irvine, CA 92697, USA; Sue and Bill Gross Stem Cell Research Center, UC Irvine, Irvine, CA 92697, USA.
  • Miyoshi E; Department of Neurobiology & Behavior, UC Irvine, Irvine, CA 92697, USA.
  • Chadarevian JP; Department of Neurobiology & Behavior, UC Irvine, Irvine, CA 92697, USA; Sue and Bill Gross Stem Cell Research Center, UC Irvine, Irvine, CA 92697, USA.
  • Claes C; Sue and Bill Gross Stem Cell Research Center, UC Irvine, Irvine, CA 92697, USA; Institute for Memory Impairments and Neurological Disorders, UC Irvine, Irvine, CA 92697, USA.
  • Coburn MA; Department of Neurobiology & Behavior, UC Irvine, Irvine, CA 92697, USA; Sue and Bill Gross Stem Cell Research Center, UC Irvine, Irvine, CA 92697, USA.
  • Hasselmann J; Department of Neurobiology & Behavior, UC Irvine, Irvine, CA 92697, USA; Sue and Bill Gross Stem Cell Research Center, UC Irvine, Irvine, CA 92697, USA.
  • Hidalgo J; Sue and Bill Gross Stem Cell Research Center, UC Irvine, Irvine, CA 92697, USA.
  • Tran KN; Sue and Bill Gross Stem Cell Research Center, UC Irvine, Irvine, CA 92697, USA.
  • Martini AC; Institute for Memory Impairments and Neurological Disorders, UC Irvine, Irvine, CA 92697, USA; Department of Pathology & Laboratory Medicine, UC Irvine, Irvine, CA 92697, USA.
  • Chang Rothermich W; Sue and Bill Gross Stem Cell Research Center, UC Irvine, Irvine, CA 92697, USA.
  • Pascual J; Institute for Memory Impairments and Neurological Disorders, UC Irvine, Irvine, CA 92697, USA; Department of Pathology & Laboratory Medicine, UC Irvine, Irvine, CA 92697, USA.
  • Head E; Institute for Memory Impairments and Neurological Disorders, UC Irvine, Irvine, CA 92697, USA; Department of Pathology & Laboratory Medicine, UC Irvine, Irvine, CA 92697, USA.
  • Hume DA; Mater Research Institute-University of Queensland, Brisbane, Australia.
  • Pridans C; University of Edinburgh Centre for Inflammation Research, Edinburgh, UK; Simons Initiative for the Developing Brain Centre, University of Edinburgh, Edinburgh, UK; The Muir Maxwell Epilepsy Centre, University of Edinburgh, Edinburgh, UK.
  • Davtyan H; Sue and Bill Gross Stem Cell Research Center, UC Irvine, Irvine, CA 92697, USA; Institute for Memory Impairments and Neurological Disorders, UC Irvine, Irvine, CA 92697, USA.
  • Swarup V; Department of Neurobiology & Behavior, UC Irvine, Irvine, CA 92697, USA; Institute for Memory Impairments and Neurological Disorders, UC Irvine, Irvine, CA 92697, USA.
  • Blurton-Jones M; Department of Neurobiology & Behavior, UC Irvine, Irvine, CA 92697, USA; Sue and Bill Gross Stem Cell Research Center, UC Irvine, Irvine, CA 92697, USA; Institute for Memory Impairments and Neurological Disorders, UC Irvine, Irvine, CA 92697, USA. Electronic address: mblurton@uci.edu.
Cell Rep ; 39(11): 110961, 2022 06 14.
Article em En | MEDLINE | ID: mdl-35705056
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Angiopatia Amiloide Cerebral / Microglia / Doença de Alzheimer Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Angiopatia Amiloide Cerebral / Microglia / Doença de Alzheimer Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article