The synergistic anticancer effect of salinomycin combined with cabazitaxel in CD44+ prostate cancer cells by downregulating wnt, NF-&#954;B and AKT signaling.

Erdogan, Suat; Serttas, Riza; Turkekul, Kader; Dibirdik, Ilker

The synergistic anticancer effect of salinomycin combined with cabazitaxel in CD44+ prostate cancer cells by downregulating wnt, NF-κB and AKT signaling.

Erdogan, Suat; Serttas, Riza; Turkekul, Kader; Dibirdik, Ilker.

Afiliação

Erdogan S; Department of Medical Biology, School of Medicine, Trakya University, Balkan Campus, Edirne, Turkey. suaterdogan@trakya.edu.tr.
Serttas R; Department of Medical Biology, School of Medicine, Trakya University, Balkan Campus, Edirne, Turkey.
Turkekul K; Department of Medical Biology, School of Medicine, Trakya University, Balkan Campus, Edirne, Turkey.
Dibirdik I; Department of Biochemistry, School of Medicine, Trakya University, Balkan Campus, Edirne, Turkey.

Mol Biol Rep ; 49(6): 4873-4884, 2022 Jun.

Article em En | MEDLINE | ID: mdl-35705771

Assuntos

Antineoplásicos; Neoplasias da Próstata; Antineoplásicos/uso terapêutico; Apoptose; Linhagem Celular Tumoral; Humanos; Receptores de Hialuronatos/metabolismo; Masculino; NF-kappa B/metabolismo; Células-Tronco Neoplásicas/metabolismo; Neoplasias da Próstata/tratamento farmacológico; Neoplasias da Próstata/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Piranos; RNA Mensageiro/metabolismo; Taxoides

Palavras-chave

Apoptosis; CD44; Cabazitaxel; Cancer stem cell; Prostate cancer; Salinomycin

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Antineoplásicos Limite: Humans / Male Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google