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Genome-wide polygenic score to predict chronic kidney disease across ancestries.
Khan, Atlas; Turchin, Michael C; Patki, Amit; Srinivasasainagendra, Vinodh; Shang, Ning; Nadukuru, Rajiv; Jones, Alana C; Malolepsza, Edyta; Dikilitas, Ozan; Kullo, Iftikhar J; Schaid, Daniel J; Karlson, Elizabeth; Ge, Tian; Meigs, James B; Smoller, Jordan W; Lange, Christoph; Crosslin, David R; Jarvik, Gail P; Bhatraju, Pavan K; Hellwege, Jacklyn N; Chandler, Paulette; Torvik, Laura Rasmussen; Fedotov, Alex; Liu, Cong; Kachulis, Christopher; Lennon, Niall; Abul-Husn, Noura S; Cho, Judy H; Ionita-Laza, Iuliana; Gharavi, Ali G; Chung, Wendy K; Hripcsak, George; Weng, Chunhua; Nadkarni, Girish; Irvin, Marguerite R; Tiwari, Hemant K; Kenny, Eimear E; Limdi, Nita A; Kiryluk, Krzysztof.
Afiliação
  • Khan A; Division of Nephrology, Department of Medicine, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, USA.
  • Turchin MC; Institute for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Patki A; Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.
  • Srinivasasainagendra V; Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.
  • Shang N; Division of Nephrology, Department of Medicine, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, USA.
  • Nadukuru R; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Jones AC; Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.
  • Malolepsza E; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Dikilitas O; Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.
  • Kullo IJ; Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.
  • Schaid DJ; Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.
  • Karlson E; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Ge T; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
  • Meigs JB; Division of General Internal Medicine, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Smoller JW; Harvard Medical School, Boston, MA, USA.
  • Lange C; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.
  • Crosslin DR; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
  • Jarvik GP; Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
  • Bhatraju PK; Division of Biomedical Informatics and Genomics, John W. Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA, USA.
  • Hellwege JN; Departments of Medicine (Medical Genetics) and Genome Sciences, University of Washington, Seattle, WA, USA.
  • Chandler P; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA, USA.
  • Torvik LR; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Fedotov A; Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Liu C; Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Kachulis C; Irving Institute for Clinical and Translational Research, Columbia University, New York, NY, USA.
  • Lennon N; Department of Biomedical Informatics, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, USA.
  • Abul-Husn NS; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Cho JH; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Ionita-Laza I; Institute for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Gharavi AG; Division of Genomic Medicine, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Chung WK; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Hripcsak G; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Weng C; Department of Biostatistics, Columbia University, New York, NY, USA.
  • Nadkarni G; Division of Nephrology, Department of Medicine, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, USA.
  • Irvin MR; Department of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA.
  • Tiwari HK; Department of Biomedical Informatics, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, USA.
  • Kenny EE; Department of Biomedical Informatics, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, USA.
  • Limdi NA; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Kiryluk K; Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.
Nat Med ; 28(7): 1412-1420, 2022 07.
Article em En | MEDLINE | ID: mdl-35710995

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Insuficiência Renal Crônica / Apolipoproteína L1 Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Insuficiência Renal Crônica / Apolipoproteína L1 Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article