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Identification of new FK866 analogues with potent anticancer activity against pancreatic cancer.
Bai, Jian-Fei; Majjigapu, Somi Reddy; Sordat, Bernard; Poty, Sophie; Vogel, Pierre; Elías-Rodríguez, Pilar; Moreno-Vargas, Antonio J; Carmona, Ana T; Caffa, Irene; Ghanem, Moustafa; Khalifa, Amr; Monacelli, Fiammetta; Cea, Michele; Robina, Inmaculada; Gajate, Consuelo; Mollinedo, Faustino; Bellotti, Axel; Nahimana, Aimable; Duchosal, Michel; Nencioni, Alessio.
Afiliação
  • Bai JF; Laboratory of Glycochemistry and Asymmetric Synthesis, Swiss Institute of Technology (EPFL), 1015, Lausanne, Switzerland.
  • Majjigapu SR; Laboratory of Glycochemistry and Asymmetric Synthesis, Swiss Institute of Technology (EPFL), 1015, Lausanne, Switzerland.
  • Sordat B; Laboratory of Glycochemistry and Asymmetric Synthesis, Swiss Institute of Technology (EPFL), 1015, Lausanne, Switzerland.
  • Poty S; Laboratory of Glycochemistry and Asymmetric Synthesis, Swiss Institute of Technology (EPFL), 1015, Lausanne, Switzerland.
  • Vogel P; Laboratory of Glycochemistry and Asymmetric Synthesis, Swiss Institute of Technology (EPFL), 1015, Lausanne, Switzerland.
  • Elías-Rodríguez P; Departamento de Química Orgánica, Facultad de Química, Universidad de Sevilla, Sevilla, 41012, Spain.
  • Moreno-Vargas AJ; Departamento de Química Orgánica, Facultad de Química, Universidad de Sevilla, Sevilla, 41012, Spain.
  • Carmona AT; Departamento de Química Orgánica, Facultad de Química, Universidad de Sevilla, Sevilla, 41012, Spain.
  • Caffa I; Department of Internal Medicine and Medical Specialties, University of Genoa, 16132, Genoa, Italy.
  • Ghanem M; Department of Internal Medicine and Medical Specialties, University of Genoa, 16132, Genoa, Italy.
  • Khalifa A; Department of Internal Medicine and Medical Specialties, University of Genoa, 16132, Genoa, Italy; Ospedale Policlinico San Martino IRCCS, Genoa, Italy.
  • Monacelli F; Department of Internal Medicine and Medical Specialties, University of Genoa, 16132, Genoa, Italy; Ospedale Policlinico San Martino IRCCS, Genoa, Italy.
  • Cea M; Department of Internal Medicine and Medical Specialties, University of Genoa, 16132, Genoa, Italy; Ospedale Policlinico San Martino IRCCS, Genoa, Italy.
  • Robina I; Departamento de Química Orgánica, Facultad de Química, Universidad de Sevilla, Sevilla, 41012, Spain.
  • Gajate C; Laboratory of Cell Death and Cancer Therapy, Department of Molecular Biomedicine Centro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain.
  • Mollinedo F; Laboratory of Cell Death and Cancer Therapy, Department of Molecular Biomedicine Centro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain.
  • Bellotti A; Central Laboratory of Hematology, Medical Laboratory and Pathology Department, Lausanne University Hospital, 1011, Lausanne, Switzerland.
  • Nahimana A; Central Laboratory of Hematology, Medical Laboratory and Pathology Department, Lausanne University Hospital, 1011, Lausanne, Switzerland.
  • Duchosal M; Central Laboratory of Hematology, Medical Laboratory and Pathology Department, Lausanne University Hospital, 1011, Lausanne, Switzerland; Service of Hematology, Oncology Department, Lausanne University Hospital, 1011, Lausanne, Switzerland.
  • Nencioni A; Department of Internal Medicine and Medical Specialties, University of Genoa, 16132, Genoa, Italy; Ospedale Policlinico San Martino IRCCS, Genoa, Italy. Electronic address: alessio.nencioni@unige.it.
Eur J Med Chem ; 239: 114504, 2022 Sep 05.
Article em En | MEDLINE | ID: mdl-35724566

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Piperidinas / Acrilamidas / Carcinoma Ductal Pancreático / Antineoplásicos Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Piperidinas / Acrilamidas / Carcinoma Ductal Pancreático / Antineoplásicos Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article