[Neurological aspects of systemic lupus erythematosus in individuals with late ontogenetic debut.]

The review presents an analysis of publications on the features of the manifestation of systemic lupus erythematosus in the elderly. The article reflects the probable causes and mechanisms of the development of neurological manifestations of the disease. The clinical picture in elderly patients is described in detail, the features of immunological indicators are noted. This article discusses various variants of lesions of the nervous system in systemic lupus erythematosus, which differ in a wide range of clinical manifestations. Neuropsychic disorders of systemic lupus erythematosus are among the least studied aspects, and can be both a manifestation of the underlying disease, including those coinciding with the processes of immunosuppression, and undesirable phenomena against the background of ongoing treatment. At the same time, knowledge of the features of neurological manifestations in SLE with a debut in late ontogenesis in comparison with the data of laboratory and instrumental examination methods allows for early diagnosis and timely prescribing adequate therapy to elderly patients.