Oxytocin treatment improves dexamethasone-induced depression-like symptoms associated with enhancement of hippocampal CREB-BDNF signaling in female mice.

Mori, Masayoshi; Shizunaga, Hiromi; Harada, Hiroyoshi; Tajiri, Yuki; Murata, Yusuke; Terada, Kazuki; Ohe, Kenji; Enjoji, Munechika

Oxytocin treatment improves dexamethasone-induced depression-like symptoms associated with enhancement of hippocampal CREB-BDNF signaling in female mice.

Mori, Masayoshi; Shizunaga, Hiromi; Harada, Hiroyoshi; Tajiri, Yuki; Murata, Yusuke; Terada, Kazuki; Ohe, Kenji; Enjoji, Munechika.

Afiliação

Mori M; Department of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan.
Shizunaga H; Department of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan.
Harada H; Department of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan.
Tajiri Y; Department of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan.
Murata Y; Department of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan.
Terada K; Division of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Himeji Dokkyo University, Himeji, Japan.
Ohe K; Department of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan.
Enjoji M; Department of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan.

Neuropsychopharmacol Rep ; 42(3): 356-361, 2022 09.

Article em En | MEDLINE | ID: mdl-35730145

Assuntos

Fator Neurotrófico Derivado do Encéfalo; Ocitocina; Animais; Antidepressivos/metabolismo; Antidepressivos/farmacologia; Fator Neurotrófico Derivado do Encéfalo/farmacologia; Proteína de Ligação ao Elemento de Resposta ao AMP Cíclico/metabolismo; Proteína de Ligação ao Elemento de Resposta ao AMP Cíclico/farmacologia; Depressão/induzido quimicamente; Depressão/tratamento farmacológico; Depressão/metabolismo; Dexametasona/metabolismo; Dexametasona/farmacologia; Modelos Animais de Doenças; Feminino; Glucocorticoides/metabolismo; Glucocorticoides/farmacologia; Hipocampo/metabolismo; Humanos; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Ocitocina/metabolismo; Ocitocina/farmacologia

Palavras-chave

depression; female; glucocorticoid; hippocampus; oxytocin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ocitocina / Fator Neurotrófico Derivado do Encéfalo Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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