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Characterization of the RNA-dependent RNA polymerase from Chikungunya virus and discovery of a novel ligand as a potential drug candidate.
Freire, Marjorie C L C; Basso, Luis G M; Mendes, Luis F S; Mesquita, Nathalya C M R; Mottin, Melina; Fernandes, Rafaela S; Policastro, Lucca R; Godoy, Andre S; Santos, Igor A; Ruiz, Uriel E A; Caruso, Icaro P; Sousa, Bruna K P; Jardim, Ana C G; Almeida, Fabio C L; Gil, Laura H V G; Andrade, Carolina H; Oliva, Glaucius.
Afiliação
  • Freire MCLC; Institute of Physics of Sao Carlos, University of Sao Paulo, Sao Carlos, SP, Brazil.
  • Basso LGM; Physical Sciences Laboratory, State University of Northern Rio de Janeiro Darcy Ribeiro (UENF), Campos dos Goytacazes, RJ, Brazil.
  • Mendes LFS; Departament of Physics, Ribeirao Preto School of Philosophy, Science and Literature, University of Sao Paulo, Ribeirao Preto, SP, Brazil.
  • Mesquita NCMR; Institute of Physics of Sao Carlos, University of Sao Paulo, Sao Carlos, SP, Brazil.
  • Mottin M; Laboratory for Molecular Modeling and Drug Design, Labmol, Faculty of Pharmacy, Universidade Federal de Goiás, Goiânia, GO, Brazil.
  • Fernandes RS; Institute of Physics of Sao Carlos, University of Sao Paulo, Sao Carlos, SP, Brazil.
  • Policastro LR; Institute of Physics of Sao Carlos, University of Sao Paulo, Sao Carlos, SP, Brazil.
  • Godoy AS; Institute of Physics of Sao Carlos, University of Sao Paulo, Sao Carlos, SP, Brazil.
  • Santos IA; Institute of Biomedical Sciences, Federal University of Uberlandia, Uberlandia, MG, Brazil.
  • Ruiz UEA; Institute of Biomedical Sciences, Federal University of Uberlandia, Uberlandia, MG, Brazil.
  • Caruso IP; Institute of Biosciences, Humanities and Exact Sciences (Ibilce), Sao Paulo State University (Unesp), Campus Sao Jose do Rio Preto, Sao Jose do Rio Preto, SP, Brazil.
  • Sousa BKP; Institute of Medical Biochemistry (IBqM) Leopoldo de Meis, National Center of Nuclear Magnetic Resonance Jiri Jonas, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
  • Jardim ACG; Laboratory for Molecular Modeling and Drug Design, Labmol, Faculty of Pharmacy, Universidade Federal de Goiás, Goiânia, GO, Brazil.
  • Almeida FCL; Institute of Biomedical Sciences, Federal University of Uberlandia, Uberlandia, MG, Brazil.
  • Gil LHVG; Institute of Biosciences, Humanities and Exact Sciences (Ibilce), Sao Paulo State University (Unesp), Campus Sao Jose do Rio Preto, Sao Jose do Rio Preto, SP, Brazil.
  • Andrade CH; Institute of Medical Biochemistry (IBqM) Leopoldo de Meis, National Center of Nuclear Magnetic Resonance Jiri Jonas, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
  • Oliva G; National Center of Nuclear Magnetic Resonance (CNRMN), Center of Structural Biology and Bioimaging (CENABIO), Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Sci Rep ; 12(1): 10601, 2022 06 22.
Article em En | MEDLINE | ID: mdl-35732685
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vírus Chikungunya / Febre de Chikungunya Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vírus Chikungunya / Febre de Chikungunya Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article