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IFT80 negatively regulates osteoclast differentiation via association with Cbl-b to disrupt TRAF6 stabilization and activation.
Deepak, Vishwa; Yang, Shu-Ting; Li, Ziqing; Li, Xinhua; Ng, Andrew; Xu, Ding; Li, Yi-Ping; Oursler, Merry Jo; Yang, Shuying.
Afiliação
  • Deepak V; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Yang ST; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Li Z; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Li X; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Ng A; Department of Oral Biology, School of Dental Medicine, State University of New York at Buffalo, Buffalo, NY 14214.
  • Xu D; Department of Oral Biology, School of Dental Medicine, State University of New York at Buffalo, Buffalo, NY 14214.
  • Li YP; Department of Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, LA 70112.
  • Oursler MJ; Robert and Arlene Kogod Center on Aging, Mayo Clinic College of Medicine, Rochester, MN 55905.
  • Yang S; Division of Endocrinology, Mayo Clinic College of Medicine, Rochester, MN 55905.
Proc Natl Acad Sci U S A ; 119(26): e2201490119, 2022 06 28.
Article em En | MEDLINE | ID: mdl-35733270
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoclastos / Osteogênese / Reabsorção Óssea / Proteínas de Transporte / Proteínas Adaptadoras de Transdução de Sinal / Fator 6 Associado a Receptor de TNF / Proteínas Proto-Oncogênicas c-cbl Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoclastos / Osteogênese / Reabsorção Óssea / Proteínas de Transporte / Proteínas Adaptadoras de Transdução de Sinal / Fator 6 Associado a Receptor de TNF / Proteínas Proto-Oncogênicas c-cbl Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article