The rs10830963 Polymorphism of the MTNR1B Gene: Association With Abnormal Glucose, Insulin and C-peptide Kinetics.

Vejrazkova, Daniela; Vankova, Marketa; Vcelak, Josef; Krejci, Hana; Anderlova, Katerina; Tura, Andrea; Pacini, Giovanni; Sumova, Alena; Sladek, Martin; Bendlova, Bela

Vejrazkova, Daniela; Vankova, Marketa; Vcelak, Josef; Krejci, Hana; Anderlova, Katerina; Tura, Andrea; Pacini, Giovanni; Sumova, Alena; Sladek, Martin; Bendlova, Bela.

Afiliação

Vejrazkova D; Department of Molecular Endocrinology, Institute of Endocrinology, Prague, Czechia.
Vankova M; Department of Molecular Endocrinology, Institute of Endocrinology, Prague, Czechia.
Vcelak J; Department of Molecular Endocrinology, Institute of Endocrinology, Prague, Czechia.
Krejci H; Department of Obstetrics and Gynecology, 1st Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czechia.
Anderlova K; Department of Obstetrics and Gynecology, 1st Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czechia.
Tura A; Metabolic Unit, Institute of Neuroscience, National Research Council, Padova, Italy.
Pacini G; Metabolic Unit, Institute of Neuroscience, National Research Council, Padova, Italy.
Sumova A; Laboratory of Biological Rhythms, Institute of Physiology of the Czech Academy of Sciences, Prague, Czechia.
Sladek M; Laboratory of Biological Rhythms, Institute of Physiology of the Czech Academy of Sciences, Prague, Czechia.
Bendlova B; Department of Molecular Endocrinology, Institute of Endocrinology, Prague, Czechia.

Front Endocrinol (Lausanne) ; 13: 868364, 2022.

Article em En | MEDLINE | ID: mdl-35733780

Assuntos

Diabetes Mellitus Tipo 2; Intolerância à Glucose; Resistência à Insulina; Estado Pré-Diabético; Receptor MT2 de Melatonina; Glicemia; Peptídeo C; Diabetes Mellitus Tipo 2/epidemiologia; Diabetes Mellitus Tipo 2/genética; Feminino; Glucagon; Glucose; Intolerância à Glucose/epidemiologia; Intolerância à Glucose/genética; Humanos; Insulina; Resistência à Insulina/genética; Cinética; Masculino; Receptor MT2 de Melatonina/genética

Palavras-chave

MTNR1B gene; OGTT trajectories; beta cell function; glucose tolerance; insulin sensitivity; rs10830963; type 2 daibetes mellitus

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estado Pré-Diabético / Resistência à Insulina / Intolerância à Glucose / Receptor MT2 de Melatonina / Diabetes Mellitus Tipo 2 Tipo de estudo: Risk_factors_studies Limite: Female / Humans / Male Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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