Repeatability of radiotherapy dose-painting prescriptions derived from a multiparametric magnetic resonance imaging model of glioblastoma infiltration.

Brighi, Caterina; Verburg, Niels; Koh, Eng-Siew; Walker, Amy; Chen, Cathy; Pillay, Sugendran; de Witt Hamer, Philip C; Aly, Farhannah; Holloway, Lois C; Keall, Paul J; Waddington, David E J

Brighi, Caterina; Verburg, Niels; Koh, Eng-Siew; Walker, Amy; Chen, Cathy; Pillay, Sugendran; de Witt Hamer, Philip C; Aly, Farhannah; Holloway, Lois C; Keall, Paul J; Waddington, David E J.

Afiliação

Brighi C; ACRF Image X Institute, Sydney School of Health Sciences, The University of Sydney, Sydney, Australia.
Verburg N; Ingham Institute for Applied Medical Research, Sydney, Australia.
Koh ES; Brain Tumor Center Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.
Walker A; Department of Neurosurgery, Amsterdam UMC, Amsterdam, The Netherlands.
Chen C; Ingham Institute for Applied Medical Research, Sydney, Australia.
Pillay S; Liverpool and Macarthur Cancer Therapy Centres, Sydney, Australia.
de Witt Hamer PC; South West Sydney Clinical Campus, University of New South Wales, Sydney, Australia.
Aly F; Ingham Institute for Applied Medical Research, Sydney, Australia.
Holloway LC; Liverpool and Macarthur Cancer Therapy Centres, Sydney, Australia.
Keall PJ; South West Sydney Clinical Campus, University of New South Wales, Sydney, Australia.
Waddington DEJ; Liverpool and Macarthur Cancer Therapy Centres, Sydney, Australia.

Phys Imaging Radiat Oncol ; 23: 8-15, 2022 Jul.

Article em En | MEDLINE | ID: mdl-35734265

Palavras-chave

ADC, apparent diffusion coefficient; CSF, cerebrospinal fluid; CTV, clinical target volume; CV, coefficient of variation; DP, dose prescription; DSC, dynamic-susceptibility contrast; Dose-painting; EORTC, European Organisation for Research and Treatment of Cancer; FLAIR, fluid-attenuated inverse recovery; GBM, glioblastoma; GTV, gross tumour volume; Glioblastoma; ICC, intraclass correlation coefficient; Multiparametric MRI; PTV, planned target volume; RC, repeatability coefficient; Radiotherapy; Repeatability; SVZ, subventricular zones; T1CE, T1-weighted post-contrast; TP, tumour probability; VOI, volume of interest; mpMRI, multiparametric MRI; rBF, relative cerebral blood flow; rBV, relative cerebral blood volume; ΔTP, difference in tumour probability between timepoint 2 and timepoint 1; σb2, between-subject variance; σw2, within-subject variance

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article