PPARÎ´ Inhibits Hyperglycemia-Triggered Senescence of Retinal Pigment Epithelial Cells by Upregulating SIRT1.

Lee, Eun Ji; Won, Jun Pil; Lee, Hyuk Gyoon; Kim, Eunsu; Hur, Jinwoo; Lee, Won Jin; Hwang, Jung Seok; Seo, Han Geuk.

Afiliação

Lee EJ; College of Sang-Huh Life Science, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Korea.
Won JP; College of Sang-Huh Life Science, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Korea.
Lee HG; College of Sang-Huh Life Science, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Korea.
Kim E; College of Sang-Huh Life Science, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Korea.
Hur J; College of Sang-Huh Life Science, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Korea.
Lee WJ; College of Sang-Huh Life Science, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Korea.
Hwang JS; College of Sang-Huh Life Science, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Korea.
Seo HG; College of Sang-Huh Life Science, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Korea.

Antioxidants (Basel) ; 11(6)2022 Jun 20.

Article em En | MEDLINE | ID: mdl-35740104

Palavras-chave

SIRT1; high glucose; peroxisome proliferator-activated receptor Î´; premature senescence; reactive oxygen species; resveratrol; retinal pigment epithelial cells; senescence-associated ß-galactosidase staining

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article