Baicalein inhibits macrophage lipid accumulation and inflammatory response by activating the PPARÎ³/LXR&#945; pathway.

Zhang, Zi-Zhen; Yu, Xiao-Hua; Tan, Wei-Hua

Baicalein inhibits macrophage lipid accumulation and inflammatory response by activating the PPARÎ³/LXRα pathway.

Zhang, Zi-Zhen; Yu, Xiao-Hua; Tan, Wei-Hua.

Afiliação

Zhang ZZ; School of Medicine, Hunan Polytechnic of Environment and Biology, Hengyang Hunan, China.
Yu XH; Institute of Clinical Medicine, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China.
Tan WH; Emergency Department, The First Affiliated Hospital of University of South China, Hengyang, Hunan, China.

Clin Exp Immunol ; 209(3): 316-325, 2022 09 29.

Article em En | MEDLINE | ID: mdl-35749304

Assuntos

Células Espumosas; PPAR gama; Colesterol/metabolismo; Flavanonas; Flavonoides/metabolismo; Flavonoides/farmacologia; Células Espumosas/metabolismo; Interleucina-6/metabolismo; Receptores X do Fígado/genética; Receptores X do Fígado/metabolismo; Macrófagos/metabolismo; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

LXRα; PPARÎ³; baicalein; inflammatory response; lipid accumulation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: PPAR gama / Células Espumosas Tipo de estudo: Risk_factors_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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