Cancer-Associated Fibroblasts Suppress CD8+ T-cell Infiltration and Confer Resistance to Immune-Checkpoint Blockade.

Jenkins, Liam; Jungwirth, Ute; Avgustinova, Alexandra; Iravani, Marjan; Mills, Adam; Haider, Syed; Harper, James; Isacke, Clare M

Jenkins, Liam; Jungwirth, Ute; Avgustinova, Alexandra; Iravani, Marjan; Mills, Adam; Haider, Syed; Harper, James; Isacke, Clare M.

Afiliação

Jenkins L; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.
Jungwirth U; Early Oncology R&D, AstraZeneca, Aaron Klug Building, Granta Park, Cambridge, UK.
Avgustinova A; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.
Iravani M; Department of Pharmacy and Pharmacology, Centre for Therapeutic Innovation, University of Bath, Bath, UK.
Mills A; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.
Haider S; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.
Harper J; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.
Isacke CM; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.

Cancer Res ; 82(16): 2904-2917, 2022 08 16.

Article em En | MEDLINE | ID: mdl-35749591

Assuntos

Fibroblastos Associados a Câncer; Neoplasias; Animais; Linfócitos T CD8-Positivos; Linhagem Celular Tumoral; Inibidores de Checkpoint Imunológico; Camundongos; Microambiente Tumoral

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fibroblastos Associados a Câncer / Neoplasias Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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