DNA methylation-based machine learning classification distinguishes pleural mesothelioma from chronic pleuritis, pleural carcinosis, and pleomorphic lung carcinomas.

Jurmeister, Philipp; Leitheiser, Maximilian; Wolkenstein, Peggy; Klauschen, Frederick; Capper, David; Brcic, Luka

Jurmeister, Philipp; Leitheiser, Maximilian; Wolkenstein, Peggy; Klauschen, Frederick; Capper, David; Brcic, Luka.

Afiliação

Jurmeister P; Institute of Pathology, Ludwig Maximilians University Hospital Munich, Munich, Germany; Institute of Pathology, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany; German Cancer Consortium (DKTK), Partner Site Munich, and German Cancer Res
Leitheiser M; Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Neuropathology, Charitéplatz 1, Berlin, Germany.
Wolkenstein P; Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Neuropathology, Charitéplatz 1, Berlin, Germany.
Klauschen F; Institute of Pathology, Ludwig Maximilians University Hospital Munich, Munich, Germany; German Cancer Consortium (DKTK), Partner Site Munich, and German Cancer Research Center (DKFZ), Heidelberg, Germany; BIFOLD - Berlin Institute for the Foundations of Learning and Data, Berlin, Germany.
Capper D; German Cancer Consortium (DKTK), Partner Site Munich, and German Cancer Research Center (DKFZ), Heidelberg, Germany; Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Neuropathology, Charitéplatz 1, Berlin, Germany.
Brcic L; Diagnostic and Research Institute of Pathology, Medical University of Graz, Graz, Austria. Electronic address: luka.brcic@medunigraz.at.

Lung Cancer ; 170: 105-113, 2022 08.

Article em En | MEDLINE | ID: mdl-35749951

Assuntos

Adenocarcinoma de Pulmão; Carcinoma Pulmonar de Células não Pequenas; Carcinoma de Células Escamosas; Neoplasias Pulmonares; Mesotelioma Maligno; Mesotelioma; Neoplasias Pleurais; Pleurisia; Adenocarcinoma de Pulmão/genética; Carcinoma Pulmonar de Células não Pequenas/genética; Carcinoma de Células Escamosas/genética; Metilação de DNA; Células Endoteliais/patologia; Humanos; Pulmão/patologia; Neoplasias Pulmonares/diagnóstico; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/patologia; Aprendizado de Máquina; Mesotelioma/diagnóstico; Mesotelioma/genética; Mesotelioma/patologia; Mesotelioma Maligno/genética; Neoplasias Pleurais/diagnóstico; Neoplasias Pleurais/genética; Neoplasias Pleurais/patologia; Pleurisia/diagnóstico; Pleurisia/genética; Proteínas Serina-Treonina Quinases; Microambiente Tumoral/genética

Palavras-chave

Chronic pleuritis; DNA methylation; Machine learning; Pleural carcinosis; Pleural mesothelioma

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pleurais / Pleurisia / Carcinoma de Células Escamosas / Carcinoma Pulmonar de Células não Pequenas / Adenocarcinoma de Pulmão / Mesotelioma Maligno / Neoplasias Pulmonares / Mesotelioma Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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