Interactions between vector competence to chikungunya virus and resistance to deltamethrin in Aedes aegypti laboratory lines?
Med Vet Entomol
; 36(4): 486-495, 2022 12.
Article
em En
| MEDLINE
| ID: mdl-35762523
ABSTRACT
The urban mosquito species Aedes aegypti is the main vector of arboviruses worldwide. Mosquito control with insecticides is the most prevalent method for preventing transmission in the absence of effective vaccines and available treatments; however, the extensive use of insecticides has led to the development of resistance in mosquito populations throughout the world, and the number of epidemics caused by arboviruses has increased. Three mosquito lines with different resistance profiles to deltamethrin were isolated in French Guiana, including one with the I1016 knock-down resistant allele. Significant differences were observed in the cumulative proportion of mosquitoes with a disseminated chikungunya virus infection over time across these lines. In addition, some genes related to resistance (CYP6BB2, CYP6N12, GST2, trypsin) were variably overexpressed in the midgut at 7 days after an infectious bloodmeal in these three lines. Our work shows that vector competence for chikungunya virus varied between Ae. aegypti laboratory lines with different deltamethrin resistance profiles. More accurate verification of the functional association between insecticide resistance and vector competence remains to be demonstrated.
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Base de dados:
MEDLINE
Assunto principal:
Arbovírus
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Vírus Chikungunya
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Aedes
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Inseticidas
Limite:
Animals
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article