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Effect of a 2-week interruption in methotrexate treatment versus continued treatment on COVID-19 booster vaccine immunity in adults with inflammatory conditions (VROOM study): a randomised, open label, superiority trial.
Abhishek, Abhishek; Boyton, Rosemary J; Peckham, Nicholas; McKnight, Áine; Coates, Laura C; Bluett, James; Barber, Vicki; Cureton, Lucy; Francis, Anne; Appelbe, Duncan; Eldridge, Lucy; Julier, Patrick; Valdes, Ana M; Brooks, Tim; Rombach, Ines; Altmann, Daniel M; Nguyen-Van-Tam, Jonathan S; Williams, Hywel C; Cook, Jonathan A.
Afiliação
  • Abhishek A; Academic Rheumatology, University of Nottingham, Nottingham, UK. Electronic address: abhishek.abhishek@nottingham.ac.uk.
  • Boyton RJ; Department of Infectious Disease, Imperial College London, London, UK; Lung Division, Royal Brompton and Harefield Hospitals, Guy's and St Thomas' National Health Service (NHS) Foundation Trust, London, UK.
  • Peckham N; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, UK; Oxford Clinical Trials Research Unit, University of Oxford, Oxford, UK.
  • McKnight Á; Blizard Institute, Centre for Genomics and Child Health, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Coates LC; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, UK; Oxford Biomedical Research Centre, Oxford, UK.
  • Bluett J; National Institute of Health and Care Research, Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Versus Arthritis Centre for Genetics and Genomics, Centre for Musculoskeletal Research, University of Manchest
  • Barber V; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, UK; Oxford Clinical Trials Research Unit, University of Oxford, Oxford, UK.
  • Cureton L; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, UK; Oxford Clinical Trials Research Unit, University of Oxford, Oxford, UK.
  • Francis A; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, UK; Oxford Clinical Trials Research Unit, University of Oxford, Oxford, UK.
  • Appelbe D; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, UK; Oxford Clinical Trials Research Unit, University of Oxford, Oxford, UK.
  • Eldridge L; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, UK; Oxford Clinical Trials Research Unit, University of Oxford, Oxford, UK.
  • Julier P; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, UK; Oxford Clinical Trials Research Unit, University of Oxford, Oxford, UK.
  • Valdes AM; Academic Rheumatology, University of Nottingham, Nottingham, UK.
  • Brooks T; UK Health Security Agency, London, UK.
  • Rombach I; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, UK; Oxford Clinical Trials Research Unit, University of Oxford, Oxford, UK.
  • Altmann DM; Department of Inflammation and Immunology, Imperial College London, London, UK.
  • Nguyen-Van-Tam JS; Population and Lifespan Health, University of Nottingham, Nottingham, UK.
  • Williams HC; Population and Lifespan Health, University of Nottingham, Nottingham, UK.
  • Cook JA; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, UK; Oxford Clinical Trials Research Unit, University of Oxford, Oxford, UK.
Lancet Respir Med ; 10(9): 840-850, 2022 09.
Article em En | MEDLINE | ID: mdl-35772416

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Psoríase / COVID-19 Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Psoríase / COVID-19 Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article