Enantiomeric Cephalotaxus alkaloids from seeds of Cephalotaxus oliveri.
Nat Prod Bioprospect
; 12(1): 24, 2022 Jul 01.
Article
em En
| MEDLINE
| ID: mdl-35778536
ABSTRACT
Five undescribed alkaloids were isolated from the seeds of Cephalotaxus oliveri along with 27 known ones. The new structures were elucidated based on spectroscopic data including 1D and 2D NMR, MS and calculated ECD spectra. Among them, (+)-acetylcephalofortine C was an enantiomeric Cephalotaxine alkaloids. The performed bioassay revealed that those alkaloids were not cytotoxic against cancer cells and had no neuroprotective properties in the HEI-OC-1 cells model.
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MEDLINE
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En
Ano de publicação:
2022
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Article