Nanoencapsulation of Ru(<i>p</i>-cymene) Complex Bearing Ginger-based Natural Product into Liposomal Nanoformulation to Improve Its Cellular Uptake and Antiproliferative Activity.

Sumithaa, Chezhiyan; Manjunathan, Tamilvelan; Mazuryk, Olga; Peters, Silda; Pillai, Renjith S; Brindell, Malgorzata; Gopinath, Pushparathinam; Ganeshpandian, Mani

Nanoencapsulation of Ru(p-cymene) Complex Bearing Ginger-based Natural Product into Liposomal Nanoformulation to Improve Its Cellular Uptake and Antiproliferative Activity.

Sumithaa, Chezhiyan; Manjunathan, Tamilvelan; Mazuryk, Olga; Peters, Silda; Pillai, Renjith S; Brindell, Malgorzata; Gopinath, Pushparathinam; Ganeshpandian, Mani.

Afiliação

Sumithaa C; Department of Chemistry, SRM Institute of Science and Technology, Kattankulathur 603 203, Tamil Nadu, India.
Manjunathan T; Department of Chemistry, SRM Institute of Science and Technology, Kattankulathur 603 203, Tamil Nadu, India.
Mazuryk O; Department of Inorganic Chemistry, Faculty of Chemistry, Jagiellonian University in Kraków, Gronostajowa 2, Krakow 30-387, Poland.
Peters S; Department of Chemistry, SRM Institute of Science and Technology, Kattankulathur 603 203, Tamil Nadu, India.
Pillai RS; Department of Chemistry, Christ University, Bangalore 560029, Karnataka, India.
Brindell M; Department of Inorganic Chemistry, Faculty of Chemistry, Jagiellonian University in Kraków, Gronostajowa 2, Krakow 30-387, Poland.
Gopinath P; Department of Chemistry, SRM Institute of Science and Technology, Kattankulathur 603 203, Tamil Nadu, India.
Ganeshpandian M; Department of Chemistry, SRM Institute of Science and Technology, Kattankulathur 603 203, Tamil Nadu, India.

ACS Appl Bio Mater ; 5(7): 3241-3256, 2022 07 18.

Article em En | MEDLINE | ID: mdl-35786838

Assuntos

Antineoplásicos; Produtos Biológicos; Melanoma; Compostos Organometálicos; Rutênio; Zingiber officinale; Antineoplásicos/farmacologia; Produtos Biológicos/farmacologia; Caspases/metabolismo; Linhagem Celular Tumoral; Proliferação de Células; Cimenos; Zingiber officinale/metabolismo; Humanos; Lipossomos/farmacologia; Estrutura Molecular; Compostos Organometálicos/farmacologia; Estudos Prospectivos; Rutênio/farmacologia

Palavras-chave

6-gingerol; ROS-generation; Ru(p-cymene) complexes; intracellular uptake; nanoencapsulation; polydiacetylene−phospholipid assembly

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos Organometálicos / Rutênio / Produtos Biológicos / Zingiber officinale / Melanoma / Antineoplásicos Tipo de estudo: Observational_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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