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Efficacy of Bisphosphonate-Conjugated Sitafloxacin in a Murine Model of S. aureus Osteomyelitis: Evidence of "Target & Release" Kinetics and Killing of Bacteria Within Canaliculi.
Ren, Youliang; Xue, Thomas; Rainbolt, Joshua; Bentley, Karen L de Mesy; Galloway, Chad A; Liu, Yuting; Cherian, Philip; Neighbors, Jeffrey; Hofstee, Marloes I; Ebetino, Frank H; Moriarty, Thomas Fintan; Sun, Shuting; Schwarz, Edward M; Xie, Chao.
Afiliação
  • Ren Y; Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, United States.
  • Xue T; Department of Orthopaedics and Rehabilitation, University of Rochester Medical Center, Rochester, NY, United States.
  • Rainbolt J; Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, United States.
  • Bentley KLM; Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, United States.
  • Galloway CA; Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, United States.
  • Liu Y; Department of Orthopaedics and Rehabilitation, University of Rochester Medical Center, Rochester, NY, United States.
  • Cherian P; Department of Pathology, University of Rochester Medical Center, Rochester, NY, United States.
  • Neighbors J; Center for Advanced Research Technologies, University of Rochester Medical Center, Rochester, NY, United States.
  • Hofstee MI; Department of Pathology, University of Rochester Medical Center, Rochester, NY, United States.
  • Ebetino FH; Center for Advanced Research Technologies, University of Rochester Medical Center, Rochester, NY, United States.
  • Moriarty TF; Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, United States.
  • Sun S; BioVinc LLC, Pasadena, CA, United States.
  • Schwarz EM; BioVinc LLC, Pasadena, CA, United States.
  • Xie C; Department of Pharmacology, Pennsylvania State University, Hershey, PA, United States.
Front Cell Infect Microbiol ; 12: 910970, 2022.
Article em En | MEDLINE | ID: mdl-35811672
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteomielite / Infecções Estafilocócicas / Staphylococcus aureus Resistente à Meticilina Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteomielite / Infecções Estafilocócicas / Staphylococcus aureus Resistente à Meticilina Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article