Antifungal evaluation and mechanistic investigations of membrane active short synthetic peptides-based amphiphiles.

Sharma, Komal; Aaghaz, Shams; Maurya, Indresh K; Rudramurthy, Shivaprakash M; Singh, Shreya; Kumar, Vinod; Tikoo, Kulbhushan; Jain, Rahul

Sharma, Komal; Aaghaz, Shams; Maurya, Indresh K; Rudramurthy, Shivaprakash M; Singh, Shreya; Kumar, Vinod; Tikoo, Kulbhushan; Jain, Rahul.

Afiliação

Sharma K; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S. A. S. Nagar, Punjab 160 062, India.
Aaghaz S; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S. A. S. Nagar, Punjab 160 062, India.
Maurya IK; Center for Infectious Diseases, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S Nagar, Punjab 160 062, India.
Rudramurthy SM; Department of Medicinal Microbiology, Postgraduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India.
Singh S; Department of Medicinal Microbiology, Postgraduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India.
Kumar V; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S Nagar, Punjab 160 062, India.
Tikoo K; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S Nagar, Punjab 160 062, India.
Jain R; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S. A. S. Nagar, Punjab 160 062, India. Electronic address: rahuljain@niper.ac.in.

Bioorg Chem ; 127: 106002, 2022 10.

Article em En | MEDLINE | ID: mdl-35816873

Assuntos

Antifúngicos; Cryptococcus neoformans; Antibacterianos/química; Antifúngicos/química; Dipeptídeos/química; Testes de Sensibilidade Microbiana; Peptídeos/química; Staphylococcus aureus

Palavras-chave

Antifungal peptides; C. neoformans; Membrane disruption; N-1-Benzyl-l-histidine; Peptide-based antibiotics; Pore formation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cryptococcus neoformans / Antifúngicos Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cryptococcus neoformans / Antifúngicos Idioma: En Ano de publicação: 2022 Tipo de documento: Article