Plant In Situ Hi-C Experimental Protocol and Bioinformatic Analysis.
Methods Mol Biol
; 2512: 217-247, 2022.
Article
em En
| MEDLINE
| ID: mdl-35818008
ABSTRACT
Hi-C enables the characterization of the 0conformation of the genome in the three-dimensional nuclear space. This technique has revolutionized our ability to detect interactions between linearly distant genomic sites on a genome-wide scale. Here, we detail a protocol to carry out in situ Hi-C in plants and describe a straightforward bioinformatics pipeline for the analysis of such data, in particular for comparing samples from different organs or conditions.
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MEDLINE
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Cromatina
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Biologia Computacional
Idioma:
En
Ano de publicação:
2022
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Article