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Crystal structures of WrbA, a spurious target of the salicylidene acylhydrazide inhibitors of type III secretion in Gram-negative pathogens, and verification of improved specificity of next-generation compounds.
Zambelloni, Riccardo; Beckham, Katherine S H; Wu, Hong-Jin; Elofsson, Mikael; Marquez, Rudi; Gabrielsen, Mads; Roe, Andrew J.
Afiliação
  • Zambelloni R; Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Glasgow, G12 8TA, UK.
  • Beckham KSH; School of Chemistry, University of Glasgow, Glasgow G12 8QQ, UK.
  • Wu HJ; Sygnature Discovery Ltd, Biocity, Discovery Building, Nottingham, NG1 1GR, UK.
  • Elofsson M; Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Glasgow, G12 8TA, UK.
  • Marquez R; EMBL Hamburg c/o DESY, Notkestraße 85, 22603 Hamburg, Germany.
  • Gabrielsen M; Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Glasgow, G12 8TA, UK.
  • Roe AJ; Umeå Centre for Microbial Research, Department of Chemistry, Umeå University, Umeå, Sweden.
Microbiology (Reading) ; 168(7)2022 07.
Article em En | MEDLINE | ID: mdl-35829699

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Yersinia pseudotuberculosis / Proteínas de Escherichia coli / Escherichia coli Êntero-Hemorrágica Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Yersinia pseudotuberculosis / Proteínas de Escherichia coli / Escherichia coli Êntero-Hemorrágica Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article