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Yerbamate Tea Consumption: A Protective Factor in Parkinson Disease.
Sáenz-Farret, Michel; Salinas-Martínez, Ana María; Zúñiga-Ramírez, Carlos; Amorín-Costábile, Ignacio; Maiola, Ricardo; Mejía-Rojas, Koni Katerin; Galeano, Martha Sady; Velázquez, Carolina; Ruiz, Gabriela; Micheli, Federico.
Afiliação
  • Sáenz-Farret M; Movement Disorders and Neurodegenerative Diseases Unit, Hospital Civil de Guadalajara "Fray Antonio Alcalde," Guadalajara.
  • Salinas-Martínez AM; Epidemiologic and Health Services Research Unit, Mexican Institute of Social Security, Monterrey, Mexico.
  • Zúñiga-Ramírez C; Movement Disorders and Neurodegenerative Diseases Unit, Hospital Civil de Guadalajara "Fray Antonio Alcalde," Guadalajara.
  • Amorín-Costábile I; Neurology Institute, Parkinson's Disease and Movement Disorders Section, Hospital de Clínicas, University of the Oriental Republic, Montevideo, Uruguay.
  • Maiola R; Parkinson's Disease and Movement Disorders Unit, Hospital de Clínicas "José de San Martín," University of Buenos Aires (UBA), Buenos Aires, Argentina.
  • Mejía-Rojas KK; Hospital Nacional "Daniel Alcidez Carrión," National University of San Marcos, Lima, Peru.
  • Galeano MS; Hospital de Clínicas, Neurology Department, National University of Asuncion (UNA), Asunción, Paraguay.
  • Velázquez C; Neurology Department, Hospital Central de IPS, Asunción, Paraguay.
  • Ruiz G; Neurology Department, Hospital Central de IPS, Asunción, Paraguay.
  • Micheli F; Division of Neurology, Parkinson's Disease and Movement Disorders Center, University of Buenos Aires (UBA), Buenos Aires, Argentina.
Clin Neuropharmacol ; 45(4): 79-83, 2022.
Article em En | MEDLINE | ID: mdl-35849689
INTRODUCTION: Little is known about the association between Yerbamate (YMT) tea consumption and Parkinson disease (PD). We determined whether there was an association between YMT tea consumption and PD. METHODS: We conducted a multicenter case-control study in 3 countries (Argentina, Paraguay, and Uruguay). We applied a structured questionnaire about YMT tea consumption history. The survey also included information about factors previously associated with a decreased and increased risk of PD, apart from medical and demographic factors. Odds ratios and 95% confidence intervals were calculated using multivariate unconditional binary logistic regression analysis. RESULTS: We included 215 cases and 219 controls. The mean age of the cases was 65.6 ± 10.5 years and that of controls was 63.1 ± 10.5 years (P < 0.02). Years of YMT tea consumption, number of liters drunk per day, and amount of YMT used for preparing the infusion were similar between cases and controls (P > 0.05), but not the number of times the YMT was added into the container (P = 0.003) and the YMT tea concentration per serving (P = 0.02). The multivariate analysis showed that YMT tea concentration per serving lowered the risk for PD, independent of potential confounders (odds ratio, 0.62; 95% confidence interval, 0.47-0.84). CONCLUSIONS: This multicenter study highlights the association between an environmental factor, the YMT tea drinking, and PD. Although more evidence from longitudinal studies is needed, the results obtained here points toward a protective effect of the YMT tea concentration per serving on PD.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Chá Tipo de estudo: Clinical_trials / Etiology_studies / Observational_studies / Qualitative_research / Risk_factors_studies Limite: Aged / Humans / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Chá Tipo de estudo: Clinical_trials / Etiology_studies / Observational_studies / Qualitative_research / Risk_factors_studies Limite: Aged / Humans / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article