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MET-PREVENT: metformin to improve physical performance in older people with sarcopenia and physical prefrailty/frailty - protocol for a double-blind, randomised controlled proof-of-concept trial.
Rennie, Katherine J; Witham, Miles; Bradley, Penny; Clegg, Andrew; Connolly, Stephen; Hancock, Helen C; Hiu, Shaun; Marsay, Leanne; McDonald, Claire; Robertson, Laura; Simms, Laura; Steel, Alison J; Steves, Claire J; Storey, Bryony; Wason, James; Wilson, Nina; von Zglinicki, Thomas; Sayer, Avan A P.
Afiliação
  • Rennie KJ; Newcastle Clinical Trials Unit, Newcastle University, Newcastle upon Tyne, UK.
  • Witham M; NIHR Newcastle Biomedical Research Centre, Newcastle University and Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK miles.witham@newcastle.ac.uk.
  • Bradley P; Pharmacy Directorate, Newcastle Upon Tyne Hospitals NHS Trust, Newcastle Upon Tyne, UK.
  • Clegg A; Academic Unit of Elderly Care & Rehabilitation, University of Leeds, Bradford, UK.
  • Connolly S; Patient and Public Involvement Representative, Newcastle upon Tyne, UK.
  • Hancock HC; Newcastle Clinical Trials Unit, Newcastle University, Newcastle upon Tyne, UK.
  • Hiu S; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
  • Marsay L; Newcastle Clinical Trials Unit, Newcastle University, Newcastle upon Tyne, UK.
  • McDonald C; Gateshead Health NHS Foundation Trust, Gateshead, UK.
  • Robertson L; Newcastle Clinical Trials Unit, Newcastle University, Newcastle upon Tyne, UK.
  • Simms L; Newcastle Clinical Trials Unit, Newcastle University, Newcastle upon Tyne, UK.
  • Steel AJ; Newcastle Clinical Trials Unit, Newcastle University, Newcastle upon Tyne, UK.
  • Steves CJ; King's College London, London, UK.
  • Storey B; Gateshead Health NHS Foundation Trust, Gateshead, UK.
  • Wason J; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
  • Wilson N; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
  • von Zglinicki T; Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
  • Sayer AAP; NIHR Newcastle Biomedical Research Centre, Newcastle University and Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
BMJ Open ; 12(7): e061823, 2022 07 18.
Article em En | MEDLINE | ID: mdl-35851031

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Treinamento Resistido / Sarcopenia / Fragilidade / Metformina Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Aged / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Treinamento Resistido / Sarcopenia / Fragilidade / Metformina Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Aged / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article